Entity Details

Primary name BRD4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESU6
EntryNameBRD4_MOUSE
FullNameBromodomain-containing protein 4
TaxID10090
Evidenceevidence at protein level
Length1400
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesBrd4

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000785 chromatin
GO:0000794 condensed nuclear chromosome
GO:0001833 inner cell mass cell proliferation
GO:0002039 p53 binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0006468 protein phosphorylation
GO:0007059 chromosome segregation
GO:0008024 cyclin/CDK positive transcription elongation factor complex
GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0034211 GTP-dependent protein kinase activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043388 positive regulation of DNA binding
GO:0043983 histone H4-K12 acetylation
GO:0044154 histone H3-K14 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0050727 regulation of inflammatory response
GO:0070577 lysine-acetylated histone binding
GO:0099122 RNA polymerase II C-terminal domain binding
GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2001255 positive regulation of histone H3-K36 trimethylation

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001487 BromodomainDomainDomain
IPR018359 Bromodomain, conserved siteSiteConserved site
IPR027353 NET domainDomainDomain
IPR031354 Bromodomain protein 4, C-terminalDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR038336 NET domain superfamilyFamilyHomologous superfamily
IPR043508 Brdt, bromodomain, repeat IDomainDomain
IPR043509 Brdt, bromodomain, repeat IIDomainDomain

Diseases

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Interactions

3 interactions