Entity Details

Primary name VAV1
Entity type gene
Source Source Link

Details

PrimaryID7409
RefseqGene
SymbolVAV1
Namevav guanine nucleotide exchange factor 1
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-07-15
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsVAV_HUMAN

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0008361 regulation of cell size
GO:0019221 cytokine-mediated signaling pathway
GO:0030168 platelet activation
GO:0030217 T cell differentiation
GO:0030593 neutrophil chemotaxis
GO:0031295 T cell costimulation
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043065 positive regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051897 positive regulation of protein kinase B signaling
GO:0072593 reactive oxygen species metabolic process
GO:0140031 phosphorylation-dependent protein binding

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
VAV1MbpBioGRID, MINT18067320 details
VAV1Khdrbs1MINT17855053 details
VAV1Plcg1MINT17050525 details