Entity Details

Primary name VAV2
Entity type gene
Source Source Link

Details

PrimaryID7410
RefseqGeneNG_029725
SymbolVAV2
Namevav guanine nucleotide exchange factor 2
Chromosome9
Location9q34.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-10-10
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsVAV2_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001525 angiogenesis
GO:0001784 phosphotyrosine residue binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0008361 regulation of cell size
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0030168 platelet activation
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043065 positive regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048013 ephrin receptor signaling pathway
GO:0051056 regulation of small GTPase mediated signal transduction

Diseases

Show/Hide Table

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
VAV2MbpBioGRID, MINT18067320 details
VAV2Cct4BioGRID, IntAct26496610 details
VAV2Ccdc12BioGRID, IntAct26496610 details
VAV2Tubg1BioGRID, IntAct26496610 details
VAV2Espl1BioGRID, IntAct26496610 details
VAV2MecomMINT30462309 details