Entity Details

Primary name VHL
Entity type gene
Source Source Link

Details

PrimaryID7428
RefseqGeneNG_008212
SymbolVHL
Namevon Hippel-Lindau tumor suppressor
Chromosome3
Location3p25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-01-15
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsVHL_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000902 cell morphogenesis
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006508 proteolysis
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0019899 enzyme binding
GO:0043066 negative regulation of apoptotic process
GO:0043687 post-translational protein modification
GO:0045597 positive regulation of cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0050821 protein stabilization
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:1990756 ubiquitin ligase-substrate adaptor activity

Diseases

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Interactions

9 interactions