Entity Details

Primary name EZR
Entity type gene
Source Source Link

Details

PrimaryID7430
RefseqGeneNG_052952
SymbolEZR
Nameezrin
Chromosome6
Location6q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-02-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEZRI_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001650 fibrillar center
GO:0001726 ruffle
GO:0001772 immunological synapse
GO:0001931 uropod
GO:0001951 intestinal D-glucose absorption
GO:0003376 sphingosine-1-phosphate receptor signaling pathway
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005903 brush border
GO:0005925 focal adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0007411 axon guidance
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
GO:0008360 regulation of cell shape
GO:0010628 positive regulation of gene expression
GO:0010737 protein kinase A signaling
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019898 extrinsic component of membrane
GO:0019904 protein domain specific binding
GO:0022614 membrane to membrane docking
GO:0030033 microvillus assembly
GO:0030175 filopodium
GO:0030315 T-tubule
GO:0030863 cortical cytoskeleton
GO:0030953 astral microtubule organization
GO:0031528 microvillus membrane
GO:0031532 actin cytoskeleton reorganization
GO:0031623 receptor internalization
GO:0031982 vesicle
GO:0032532 regulation of microvillus length
GO:0032587 ruffle membrane
GO:0032703 negative regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0034236 protein kinase A catalytic subunit binding
GO:0034237 protein kinase A regulatory subunit binding
GO:0034629 cellular protein-containing complex localization
GO:0035088 establishment or maintenance of apical/basal cell polarity
GO:0036064 ciliary basal body
GO:0040018 positive regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0043622 cortical microtubule organization
GO:0044297 cell body
GO:0044393 microspike
GO:0044548 S100 protein binding
GO:0044853 plasma membrane raft
GO:0045177 apical part of cell
GO:0045296 cadherin binding
GO:0046847 filopodium assembly
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048471 perinuclear region of cytoplasm
GO:0050714 positive regulation of protein secretion
GO:0050839 cell adhesion molecule binding
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly
GO:0051018 protein kinase A binding
GO:0051117 ATPase binding
GO:0051286 cell tip
GO:0051660 establishment of centrosome localization
GO:0061028 establishment of endothelial barrier
GO:0070062 extracellular exosome
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071320 cellular response to cAMP
GO:0071944 cell periphery
GO:0072659 protein localization to plasma membrane
GO:0072697 protein localization to cell cortex
GO:0097449 astrocyte projection
GO:0097454 Schwann cell microvillus
GO:0097718 disordered domain specific binding
GO:0098592 cytoplasmic side of apical plasma membrane
GO:1902115 regulation of organelle assembly
GO:1902896 terminal web assembly
GO:1902966 positive regulation of protein localization to early endosome
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903364 positive regulation of cellular protein catabolic process
GO:1903753 negative regulation of p38MAPK cascade
GO:2000643 positive regulation of early endosome to late endosome transport

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
EZRMap4k4DIP16938849 details
EZRTsc1BioGRID10806479 details
EZRCdk1BioGRID, IntAct20360068 details
EZRMsnBioGRID, IntAct26496610 details
EZRMecomMINT30462309 details
EZRArhgap28BioGRID, IntAct32203420 details
EZRMdm2BioGRID24980433 details