Entity Details

Primary name DKC1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9ESX5
EntryNameDKC1_MOUSE
FullNameH/ACA ribonucleoprotein complex subunit DKC1
TaxID10090
Evidenceevidence at protein level
Length509
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesDkc1

GO terms

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GOName
GO:0000454 snoRNA guided rRNA pseudouridine synthesis
GO:0000455 enzyme-directed rRNA pseudouridine synthesis
GO:0000495 box H/ACA RNA 3'-end processing
GO:0001650 fibrillar center
GO:0003720 telomerase activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005697 telomerase holoenzyme complex
GO:0005730 nucleolus
GO:0007004 telomere maintenance via telomerase
GO:0008284 positive regulation of cell population proliferation
GO:0009982 pseudouridine synthase activity
GO:0015030 Cajal body
GO:0031118 rRNA pseudouridine synthesis
GO:0031120 snRNA pseudouridine synthesis
GO:0031429 box H/ACA snoRNP complex
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0033979 box H/ACA RNA metabolic process
GO:0034513 box H/ACA snoRNA binding
GO:0051973 positive regulation of telomerase activity
GO:0070034 telomerase RNA binding
GO:0090661 box H/ACA telomerase RNP complex
GO:0090666 scaRNA localization to Cajal body
GO:0090669 telomerase RNA stabilization
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904872 regulation of telomerase RNA localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body
GO:1990481 mRNA pseudouridine synthesis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002478 PUA domainDomainDomain
IPR002501 Pseudouridine synthase II, N-terminalDomainDomain
IPR004521 Uncharacterised domain CHP00451DomainDomain
IPR004802 tRNA pseudouridine synthase B familyFamilyFamily
IPR012960 Dyskerin-likeDomainDomain
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR020103 Pseudouridine synthase, catalytic domain superfamilyFamilyHomologous superfamily
IPR032819 tRNA pseudouridylate synthase B, C-terminalDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DKC1_MOUSEFBRL_MOUSEMINT23726835 details