Entity Details

Primary name XRCC1
Entity type gene
Source Source Link

Details

PrimaryID7515
RefseqGeneNG_033799
SymbolXRCC1
NameX-ray repair cross complementing 1
Chromosome19
Location19q13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-07-08
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsXRCC1_HUMAN

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006284 base-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006288 base-excision repair, DNA ligation
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0010033 response to organic substance
GO:0010836 negative regulation of protein ADP-ribosylation
GO:0019899 enzyme binding
GO:0021587 cerebellum morphogenesis
GO:0021766 hippocampus development
GO:0032356 oxidized DNA binding
GO:0033194 response to hydroperoxide
GO:0042493 response to drug
GO:0050882 voluntary musculoskeletal movement
GO:0061819 telomeric DNA-containing double minutes formation
GO:0070522 ERCC4-ERCC1 complex
GO:1903518 positive regulation of single strand break repair
GO:1904877 positive regulation of DNA ligase activity
GO:1905765 negative regulation of protection from non-homologous end joining at telomere
GO:1990414 replication-born double-strand break repair via sister chromatid exchange
GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
XRCC1Tpx2BioGRID, IntAct26496610 details
XRCC1PrkciBioGRID, IntAct26496610 details
XRCC1JunbBioGRID, IntAct26496610 details