Entity Details

Primary name CXCR4
Entity type gene
Source Source Link

Details

PrimaryID7852
RefseqGeneNG_011587
SymbolCXCR4
NameC-X-C motif chemokine receptor 4
Chromosome2
Location2q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-09-21
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCXCR4_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001618 virus receptor activity
GO:0001666 response to hypoxia
GO:0001764 neuron migration
GO:0002064 epithelial cell development
GO:0002407 dendritic cell chemotaxis
GO:0003779 actin binding
GO:0004930 G protein-coupled receptor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007411 axon guidance
GO:0007420 brain development
GO:0008038 neuron recognition
GO:0009615 response to virus
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0014823 response to activity
GO:0015026 coreceptor activity
GO:0016021 integral component of membrane
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0022008 neurogenesis
GO:0022029 telencephalon cell migration
GO:0030054 cell junction
GO:0030155 regulation of cell adhesion
GO:0031252 cell leading edge
GO:0031410 cytoplasmic vesicle
GO:0031625 ubiquitin protein ligase binding
GO:0032027 myosin light chain binding
GO:0032991 protein-containing complex
GO:0035470 positive regulation of vascular wound healing
GO:0035690 cellular response to drug
GO:0038147 C-X-C motif chemokine 12 receptor activity
GO:0038160 CXCL12-activated CXCR4 signaling pathway
GO:0043067 regulation of programmed cell death
GO:0043130 ubiquitin binding
GO:0043217 myelin maintenance
GO:0043278 response to morphine
GO:0044409 entry into host
GO:0045446 endothelial cell differentiation
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050792 regulation of viral process
GO:0050920 regulation of chemotaxis
GO:0050921 positive regulation of chemotaxis
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051924 regulation of calcium ion transport
GO:0060048 cardiac muscle contraction
GO:0060326 cell chemotaxis
GO:0061154 endothelial tube morphogenesis
GO:0070062 extracellular exosome
GO:0071345 cellular response to cytokine stimulus
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1903861 positive regulation of dendrite extension
GO:1905322 positive regulation of mesenchymal stem cell migration
GO:1990478 response to ultrasound
GO:2000448 positive regulation of macrophage migration inhibitory factor signaling pathway

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CXCR4Kcnk1BioGRID, IntAct26496610 details