Entity Details

Primary name USP7
Entity type gene
Source Source Link

Details

PrimaryID7874
RefseqGeneNG_046847
SymbolUSP7
Nameubiquitin specific peptidase 7
Chromosome16
Location16p13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-02-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsUBP7_HUMAN

GO terms

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GOName
GO:0002039 p53 binding
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006111 regulation of gluconeogenesis
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007275 multicellular organism development
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0010216 maintenance of DNA methylation
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0016579 protein deubiquitination
GO:0016604 nuclear body
GO:0016605 PML body
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0035520 monoubiquitinated protein deubiquitination
GO:0035616 histone H2B conserved C-terminal lysine deubiquitination
GO:0042752 regulation of circadian rhythm
GO:0048511 rhythmic process
GO:0050821 protein stabilization
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0070536 protein K63-linked deubiquitination
GO:0101005 deubiquitinase activity
GO:1901537 positive regulation of DNA demethylation
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1904353 regulation of telomere capping
GO:1905279 regulation of retrograde transport, endosome to Golgi
GO:1990380 Lys48-specific deubiquitinase activity

Diseases

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Interactions

12 interactions

InteractorPartnerSourcesPublicationsLink
USP7Bmi1MINT20601937 details
USP7Rnf2MINT20601937 details
USP7Pcgf2MINT20601937 details
USP7Mdm4I2D, IntAct15916963 20697359 details
USP7Mdm2BioGRID, I2D20697359 29581288 details
USP7Cd2apBioGRID, IntAct26496610 details
USP7Pcgf1BioGRID, IntAct26496610 details
USP7Brwd3BioGRID, IntAct26496610 details
USP7GpkowBioGRID, IntAct26496610 details
USP7JupBioGRID, IntAct26496610 details
USP7Ring1BioGRID, IntAct26496610 details
USP7Stard13BioGRID, IntAct32203420 details