Entity Details

Primary name STK4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JI11
EntryNameSTK4_MOUSE
FullNameSerine/threonine-protein kinase 4
TaxID10090
Evidenceevidence at protein level
Length487
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesStk4

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000902 cell morphogenesis
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001841 neural tube formation
GO:0001934 positive regulation of protein phosphorylation
GO:0003157 endocardium development
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007417 central nervous system development
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0016604 nuclear body
GO:0018105 peptidyl-serine phosphorylation
GO:0030216 keratinocyte differentiation
GO:0031098 stress-activated protein kinase signaling cascade
GO:0032092 positive regulation of protein binding
GO:0032147 activation of protein kinase activity
GO:0032991 protein-containing complex
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035329 hippo signaling
GO:0035556 intracellular signal transduction
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0045600 positive regulation of fat cell differentiation
GO:0046621 negative regulation of organ growth
GO:0046777 protein autophosphorylation
GO:0050821 protein stabilization
GO:0060215 primitive hemopoiesis
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0060800 regulation of cell differentiation involved in embryonic placenta development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097284 hepatocyte apoptotic process
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011524 SARAH domainDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR024205 Mst1 SARAH domainDomainDomain

Diseases

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