Entity Details

Primary name FOXL2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88470
EntryNameFOXL2_MOUSE
FullNameForkhead box protein L2
TaxID10090
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesFoxl2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001541 ovarian follicle development
GO:0002074 extraocular skeletal muscle development
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006309 apoptotic DNA fragmentation
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007338 single fertilization
GO:0008585 female gonad development
GO:0009653 anatomical structure morphogenesis
GO:0019101 female somatic sex determination
GO:0030154 cell differentiation
GO:0030331 estrogen receptor binding
GO:0031624 ubiquitin conjugating enzyme binding
GO:0033686 positive regulation of luteinizing hormone secretion
GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046881 positive regulation of follicle-stimulating hormone secretion
GO:0048048 embryonic eye morphogenesis
GO:0060014 granulosa cell differentiation
GO:0060065 uterus development
GO:0090543 Flemming body
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR018122 Fork head domain conserved site1SiteConserved site
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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