Entity Details

Primary name KMT2D
Entity type gene
Source Source Link

Details

PrimaryID8085
RefseqGeneNG_027827
SymbolKMT2D
Namelysine methyltransferase 2D
Chromosome12
Location12q13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsKMT2D_HUMAN

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0001555 oocyte growth
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006342 chromatin silencing
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell population proliferation
GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
GO:0035097 histone methyltransferase complex
GO:0042393 histone binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0043627 response to estrogen
GO:0044648 histone H3-K4 dimethylation
GO:0044666 MLL3/4 complex
GO:0045652 regulation of megakaryocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048477 oogenesis
GO:0051568 histone H3-K4 methylation
GO:0080182 histone H3-K4 trimethylation
GO:0097692 histone H3-K4 monomethylation
GO:1904837 beta-catenin-TCF complex assembly

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
KMT2DCdc6BioGRID, IntAct26496610 details
KMT2DWdr5BioGRID, IntAct26496610 details
KMT2DSetd3BioGRID, IntAct26496610 details
KMT2DPaxip1UniProt17500065 17925232 details
KMT2DTfap2dDIP18495928 details