Entity Details

Primary name CALR
Entity type gene
Source Source Link

Details

PrimaryID811
RefseqGeneNG_029662
SymbolCALR
Namecalreticulin
Chromosome19
Location19p13.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-12
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCALR_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001669 acrosomal vesicle
GO:0001849 complement component C1q complex binding
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002502 peptide antigen assembly with MHC class I protein complex
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005178 integrin binding
GO:0005506 iron ion binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005790 smooth endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005844 polysome
GO:0005925 focal adhesion
GO:0006355 regulation of transcription, DNA-templated
GO:0006457 protein folding
GO:0006611 protein export from nucleus
GO:0006874 cellular calcium ion homeostasis
GO:0006898 receptor-mediated endocytosis
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010595 positive regulation of endothelial cell migration
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0022417 protein maturation by protein folding
GO:0030133 transport vesicle
GO:0030246 carbohydrate binding
GO:0030670 phagocytic vesicle membrane
GO:0030866 cortical actin cytoskeleton organization
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0031625 ubiquitin protein ligase binding
GO:0032355 response to estradiol
GO:0033018 sarcoplasmic reticulum lumen
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway
GO:0033574 response to testosterone
GO:0034504 protein localization to nucleus
GO:0034975 protein folding in endoplasmic reticulum
GO:0036500 ATF6-mediated unfolded protein response
GO:0040020 regulation of meiotic nuclear division
GO:0042277 peptide binding
GO:0042493 response to drug
GO:0042562 hormone binding
GO:0042824 MHC class I peptide loading complex
GO:0042921 glucocorticoid receptor signaling pathway
GO:0042981 regulation of apoptotic process
GO:0044183 protein folding chaperone
GO:0044322 endoplasmic reticulum quality control compartment
GO:0045665 negative regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0050681 androgen receptor binding
GO:0050766 positive regulation of phagocytosis
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
GO:0051208 sequestering of calcium ion
GO:0055007 cardiac muscle cell differentiation
GO:0060473 cortical granule
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071285 cellular response to lithium ion
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
GO:0071682 endocytic vesicle lumen
GO:0090398 cellular senescence
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901164 negative regulation of trophoblast cell migration
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane
GO:2000510 positive regulation of dendritic cell chemotaxis

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CALRAI837181BioGRID, IntAct20360068 details
CALREdem2IntAct22665516 details
CALREdem1IntAct22665516 details