Entity Details

Primary name IF2B1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88477
EntryNameIF2B1_MOUSE
FullNameInsulin-like growth factor 2 mRNA-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length577
SequenceStatuscomplete
DateCreated2007-04-03
DateModified2021-06-02

Ontological Relatives

GenesIgf2bp1

GO terms

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GOName
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006403 RNA localization
GO:0007399 nervous system development
GO:0010468 regulation of gene expression
GO:0010494 cytoplasmic stress granule
GO:0010610 regulation of mRNA stability involved in response to stress
GO:0017148 negative regulation of translation
GO:0022013 pallium cell proliferation in forebrain
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0045182 translation regulator activity
GO:0048027 mRNA 5'-UTR binding
GO:0048471 perinuclear region of cytoplasm
GO:0051028 mRNA transport
GO:0051252 regulation of RNA metabolic process
GO:0070934 CRD-mediated mRNA stabilization
GO:0070937 CRD-mediated mRNA stability complex
GO:0097150 neuronal stem cell population maintenance
GO:0140059 dendrite arborization
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR004087 K Homology domainDomainDomain
IPR004088 K Homology domain, type 1DomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034837 IGF2BP1, RNA recognition motif 1DomainDomain
IPR034842 IGF2BP1, RNA recognition motif 2DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR036612 K Homology domain, type 1 superfamilyFamilyHomologous superfamily

Diseases

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