Entity Details

Primary name SH2B2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JID9
EntryNameSH2B2_MOUSE
FullNameSH2B adapter protein 2
TaxID10090
Evidenceevidence at protein level
Length621
SequenceStatuscomplete
DateCreated2003-08-15
DateModified2021-06-02

Ontological Relatives

GenesSh2b2

GO terms

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GOName
GO:0001725 stress fiber
GO:0001726 ruffle
GO:0001922 B-1 B cell homeostasis
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005737 cytoplasm
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0007399 nervous system development
GO:0008286 insulin receptor signaling pathway
GO:0019221 cytokine-mediated signaling pathway
GO:0019222 regulation of metabolic process
GO:0030036 actin cytoskeleton organization
GO:0035556 intracellular signal transduction
GO:0035591 signaling adaptor activity
GO:0042169 SH2 domain binding
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0046325 negative regulation of glucose import
GO:0046578 regulation of Ras protein signal transduction
GO:0050776 regulation of immune response
GO:0050851 antigen receptor-mediated signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0050873 brown fat cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015012 Phenylalanine zipperDomainDomain
IPR030520 SH2B adapter protein 2FamilyFamily
IPR030523 SH2B adapter proteinFamilyFamily
IPR035058 SH2B2, SH2 domainDomainDomain
IPR036290 Phenylalanine zipper superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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