Entity Details

Primary name AK1A1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JII6
EntryNameAK1A1_MOUSE
FullNameAldo-keto reductase family 1 member A1
TaxID10090
Evidenceevidence at protein level
Length325
SequenceStatuscomplete
DateCreated2002-08-30
DateModified2021-06-02

Ontological Relatives

GenesAkr1a1

GO terms

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GOName
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0005829 cytosol
GO:0008106 alcohol dehydrogenase (NADP+) activity
GO:0016324 apical plasma membrane
GO:0019726 mevaldate reductase (NADPH) activity
GO:0019853 L-ascorbic acid biosynthetic process
GO:0042840 D-glucuronate catabolic process
GO:0044597 daunorubicin metabolic process
GO:0044598 doxorubicin metabolic process
GO:0045202 synapse
GO:0046185 aldehyde catabolic process
GO:0047655 allyl-alcohol dehydrogenase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0047939 L-glucuronate reductase activity
GO:0047941 glucuronolactone reductase activity
GO:0047956 glycerol dehydrogenase [NADP+] activity
GO:0110095 cellular detoxification of aldehyde
GO:1990002 methylglyoxal reductase (NADPH-dependent, acetol producing)

Subcellular Location

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Subcellular Location
Apical cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily
IPR044481 Aldo-keto reductase family 1 member A1FamilyFamily

Diseases

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Interactions

0 interactions

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