Entity Details

Primary name NSD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88491
EntryNameNSD1_MOUSE
FullNameHistone-lysine N-methyltransferase, H3 lysine-36 specific
TaxID10090
Evidenceevidence at protein level
Length2588
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000414 regulation of histone H3-K36 methylation
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001702 gastrulation with mouth forming second
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0008270 zinc ion binding
GO:0016571 histone methylation
GO:0030331 estrogen receptor binding
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0035097 histone methyltransferase complex
GO:0042054 histone methyltransferase activity
GO:0042799 histone methyltransferase activity (H4-K20 specific)
GO:0042974 retinoic acid receptor binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046965 retinoid X receptor binding
GO:0046966 thyroid hormone receptor binding
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0050681 androgen receptor binding
GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000313 PWWP domainDomainDomain
IPR001214 SET domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR006560 AWS domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR041306 NSD, Cys-His rich domainDomainDomain

Diseases

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Interactions

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