Entity Details

Primary name OBSCN
Entity type gene
Source Source Link

Details

PrimaryID84033
RefseqGeneNG_032122
SymbolOBSCN
Nameobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Chromosome1
Location1q42.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-11
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsOBSCN_HUMAN

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007275 multicellular organism development
GO:0008307 structural constituent of muscle
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0016604 nuclear body
GO:0030016 myofibril
GO:0030018 Z disc
GO:0030506 ankyrin binding
GO:0031430 M band
GO:0031432 titin binding
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0036309 protein localization to M-band
GO:0042383 sarcolemma
GO:0043065 positive regulation of apoptotic process
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0045214 sarcomere organization
GO:0046872 metal ion binding
GO:0050839 cell adhesion molecule binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0098609 cell-cell adhesion
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
OBSCNSmc3BioGRID, IntAct26496610 details
OBSCNActr1bBioGRID, IntAct26496610 details
OBSCNSetd2BioGRID, IntAct26496610 details
OBSCNChmp4bBioGRID, IntAct26496610 details
OBSCNVps28BioGRID, IntAct26496610 details