Entity Details

Primary name HTRA2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JIY5
EntryNameHTRA2_MOUSE
FullNameSerine protease HTRA2, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length458
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesHtra2

GO terms

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GOName
GO:0000785 chromatin
GO:0004252 serine-type endopeptidase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006508 proteolysis
GO:0006672 ceramide metabolic process
GO:0007005 mitochondrion organization
GO:0007568 aging
GO:0007628 adult walking behavior
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0008344 adult locomotory behavior
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009635 response to herbicide
GO:0009898 cytoplasmic side of plasma membrane
GO:0010822 positive regulation of mitochondrion organization
GO:0012501 programmed cell death
GO:0016020 membrane
GO:0019742 pentacyclic triterpenoid metabolic process
GO:0030900 forebrain development
GO:0031966 mitochondrial membrane
GO:0034599 cellular response to oxidative stress
GO:0034605 cellular response to heat
GO:0035458 cellular response to interferon-beta
GO:0035631 CD40 receptor complex
GO:0040014 regulation of multicellular organism growth
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044257 cellular protein catabolic process
GO:0048666 neuron development
GO:0060548 negative regulation of cell death
GO:0071300 cellular response to retinoic acid
GO:0071363 cellular response to growth factor stimulus
GO:0097193 intrinsic apoptotic signaling pathway
GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization
GO:1905370 serine-type endopeptidase complex
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion intermembrane space
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR001940 Peptidase S1CFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR041489 PDZ domain 6DomainDomain

Diseases

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