Entity Details

Primary name NCK2
Entity type gene
Source Source Link

Details

PrimaryID8440
RefseqGene
SymbolNCK2
NameNCK adaptor protein 2
Chromosome2
Location2q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-07
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsNCK2_HUMAN

GO terms

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GOName
GO:0001771 immunological synapse formation
GO:0001784 phosphotyrosine residue binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0007015 actin filament organization
GO:0007165 signal transduction
GO:0007172 signal complex assembly
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007176 regulation of epidermal growth factor-activated receptor activity
GO:0008093 cytoskeletal anchor activity
GO:0008285 negative regulation of cell population proliferation
GO:0012506 vesicle membrane
GO:0014069 postsynaptic density
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0030159 signaling receptor complex adaptor activity
GO:0030838 positive regulation of actin filament polymerization
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0035591 signaling adaptor activity
GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress
GO:0042102 positive regulation of T cell proliferation
GO:0042110 T cell activation
GO:0044877 protein-containing complex binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048013 ephrin receptor signaling pathway
GO:0060996 dendritic spine development
GO:0097110 scaffold protein binding
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NCK2PdgfrbBioGRID9843575 details