Entity Details

Primary name TRIM5
Entity type gene
Source Source Link

Details

PrimaryID85363
RefseqGeneNG_029122
SymbolTRIM5
Nametripartite motif containing 5
Chromosome11
Location11p15.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-06-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTRIM5_HUMAN

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0000932 P-body
GO:0002218 activation of innate immune response
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006914 autophagy
GO:0008270 zinc ion binding
GO:0010468 regulation of gene expression
GO:0010508 positive regulation of autophagy
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0019901 protein kinase binding
GO:0030674 protein-macromolecule adaptor activity
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway
GO:0032880 regulation of protein localization
GO:0038187 pattern recognition receptor activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410 positive regulation of MAPK cascade
GO:0045087 innate immune response
GO:0046596 regulation of viral entry into host cell
GO:0046597 negative regulation of viral entry into host cell
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:1902187 negative regulation of viral release from host cell

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TRIM5Ppp2caBioGRID, IntAct26496610 details
TRIM5Xpo1IntAct26673895 details