Entity Details

Primary name CAV1
Entity type gene
Source Source Link

Details

PrimaryID857
RefseqGeneNG_012051
SymbolCAV1
Namecaveolin 1
Chromosome7
Location7q31.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCAV1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000139 Golgi membrane
GO:0000188 obsolete inactivation of MAPK activity
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001666 response to hypoxia
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0002080 acrosomal membrane
GO:0002095 caveolar macromolecular signaling complex
GO:0002931 response to ischemia
GO:0003057 regulation of the force of heart contraction by chemical signal
GO:0005102 signaling receptor binding
GO:0005113 patched binding
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005811 lipid droplet
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0005929 cilium
GO:0005938 cell cortex
GO:0006641 triglyceride metabolic process
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006940 regulation of smooth muscle contraction
GO:0007519 skeletal muscle tissue development
GO:0007595 lactation
GO:0008104 protein localization
GO:0009267 cellular response to starvation
GO:0009617 response to bacterium
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010608 posttranscriptional regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010875 positive regulation of cholesterol efflux
GO:0015031 protein transport
GO:0015485 cholesterol binding
GO:0016020 membrane
GO:0016050 vesicle organization
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016504 peptidase activator activity
GO:0019065 receptor-mediated endocytosis of virus by host cell
GO:0019217 regulation of fatty acid metabolic process
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019915 lipid storage
GO:0030154 cell differentiation
GO:0030193 regulation of blood coagulation
GO:0030301 cholesterol transport
GO:0030335 positive regulation of cell migration
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0030666 endocytic vesicle membrane
GO:0030674 protein-macromolecule adaptor activity
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030879 mammary gland development
GO:0031267 small GTPase binding
GO:0031295 T cell costimulation
GO:0031397 negative regulation of protein ubiquitination
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0031901 early endosome membrane
GO:0032091 negative regulation of protein binding
GO:0032092 positive regulation of protein binding
GO:0032507 maintenance of protein location in cell
GO:0032570 response to progesterone
GO:0032991 protein-containing complex
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033484 nitric oxide homeostasis
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
GO:0038016 insulin receptor internalization
GO:0042310 vasoconstriction
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0042632 cholesterol homeostasis
GO:0042802 identical protein binding
GO:0043085 positive regulation of catalytic activity
GO:0043409 negative regulation of MAPK cascade
GO:0043627 response to estrogen
GO:0044325 transmembrane transporter binding
GO:0044860 protein localization to plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045121 membrane raft
GO:0045907 positive regulation of vasoconstriction
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0048550 negative regulation of pinocytosis
GO:0050900 leukocyte migration
GO:0050998 nitric-oxide synthase binding
GO:0050999 regulation of nitric-oxide synthase activity
GO:0051001 negative regulation of nitric-oxide synthase activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051117 ATPase binding
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051592 response to calcium ion
GO:0051899 membrane depolarization
GO:0052547 regulation of peptidase activity
GO:0055074 calcium ion homeostasis
GO:0060056 mammary gland involution
GO:0060090 molecular adaptor activity
GO:0060355 positive regulation of cell adhesion molecule production
GO:0060546 negative regulation of necroptotic process
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070320 inward rectifier potassium channel inhibitor activity
GO:0070836 caveola assembly
GO:0071360 cellular response to exogenous dsRNA
GO:0071375 cellular response to peptide hormone stimulus
GO:0071455 cellular response to hyperoxia
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071711 basement membrane organization
GO:0072584 caveolin-mediated endocytosis
GO:0086091 regulation of heart rate by cardiac conduction
GO:0086098 angiotensin-activated signaling pathway involved in heart process
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097190 apoptotic signaling pathway
GO:0098903 regulation of membrane repolarization during action potential
GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900027 regulation of ruffle assembly
GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1903361 protein localization to basolateral plasma membrane
GO:1903598 positive regulation of gap junction assembly
GO:1903609 negative regulation of inward rectifier potassium channel activity
GO:1904886 beta-catenin destruction complex disassembly
GO:2000286 receptor internalization involved in canonical Wnt signaling pathway
GO:2000535 regulation of entry of bacterium into host cell
GO:2000811 negative regulation of anoikis
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

20 interactions

InteractorPartnerSourcesPublicationsLink
CAV1Grb7MINT11075810 details
CAV1SncaBioGRID21693152 details
CAV1VcpBioGRID24089527 details
CAV1Bmpr1aBioGRID, IntAct26496610 details
CAV1Rab5cBioGRID, IntAct26496610 details
CAV1Rmdn3BioGRID, IntAct26496610 details
CAV1Flot2BioGRID, IntAct26496610 details
CAV1Kcnk1BioGRID, IntAct26496610 details
CAV1Cd2apBioGRID, IntAct26496610 details
CAV1Chmp4bBioGRID, IntAct26496610 details
CAV1Lima1BioGRID, IntAct26496610 details
CAV1Tapt1BioGRID, IntAct26496610 details
CAV1SpastBioGRID, IntAct26496610 details
CAV1Tsg101BioGRID, IntAct26496610 details
CAV1Ptpn23BioGRID, IntAct26496610 details
CAV1Tmed2BioGRID, IntAct26496610 details
CAV1JunbBioGRID, IntAct26496610 details
CAV1Prdm16MINT30462309 details
CAV1MecomMINT30462309 details
CAV1Coro1cBioGRID26496610 details