Entity Details

Primary name RUNX1
Entity type gene
Source Source Link

Details

PrimaryID861
RefseqGeneNG_011402
SymbolRUNX1
NameRUNX family transcription factor 1
Chromosome21
Location21q22.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-09
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsRUNX1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001503 ossification
GO:0001959 regulation of cytokine-mediated signaling pathway
GO:0002062 chondrocyte differentiation
GO:0002573 myeloid leukocyte differentiation
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0010629 negative regulation of gene expression
GO:0010755 regulation of plasminogen activation
GO:0016513 core-binding factor complex
GO:0030097 hemopoiesis
GO:0030099 myeloid cell differentiation
GO:0030111 regulation of Wnt signaling pathway
GO:0030182 neuron differentiation
GO:0030853 negative regulation of granulocyte differentiation
GO:0030854 positive regulation of granulocyte differentiation
GO:0032743 positive regulation of interleukin-2 production
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033146 regulation of intracellular estrogen receptor signaling pathway
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0045589 regulation of regulatory T cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045616 regulation of keratinocyte differentiation
GO:0045637 regulation of myeloid cell differentiation
GO:0045652 regulation of megakaryocyte differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048935 peripheral nervous system neuron development
GO:0050855 regulation of B cell receptor signaling pathway
GO:0060043 regulation of cardiac muscle cell proliferation
GO:0061026 cardiac muscle tissue regeneration
GO:0071425 hematopoietic stem cell proliferation
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1903055 positive regulation of extracellular matrix organization
GO:1905203 regulation of connective tissue replacement
GO:2000810 regulation of bicellular tight junction assembly

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
RUNX1CbfbBioGRID25066130 details
RUNX1Hipk2BioGRID30755814 details
RUNX1Cep72BioGRID, IntAct26496610 details
RUNX1MecomMINT30462309 details