Entity Details

Primary name TNFSF10
Entity type gene
Source Source Link

Details

PrimaryID8743
RefseqGene
SymbolTNFSF10
NameTNF superfamily member 10
Chromosome3
Location3q26.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-11
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsTNF10_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0032868 response to insulin
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045569 TRAIL binding
GO:0070062 extracellular exosome
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TNFSF10FaddMINT21627969 details
TNFSF10Ripk1MINT21627969 details