Entity Details

Primary name RIPK2
Entity type gene
Source Source Link

Details

PrimaryID8767
RefseqGeneNG_033016
SymbolRIPK2
Namereceptor interacting serine/threonine kinase 2
Chromosome8
Location8q21.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-07
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsRIPK2_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0002250 adaptive immune response
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004706 JUN kinase kinase kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0007257 obsolete activation of JUN kinase activity
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0010942 positive regulation of cell death
GO:0030274 LIM domain binding
GO:0031398 positive regulation of protein ubiquitination
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031982 vesicle
GO:0032092 positive regulation of protein binding
GO:0032722 positive regulation of chemokine production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032735 positive regulation of interleukin-12 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0033091 positive regulation of immature T cell proliferation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034134 toll-like receptor 2 signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0042098 T cell proliferation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0050700 CARD domain binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050830 defense response to Gram-positive bacterium
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070671 response to interleukin-12
GO:0070673 response to interleukin-18
GO:0071223 cellular response to lipoteichoic acid
GO:0071224 cellular response to peptidoglycan
GO:0071225 cellular response to muramyl dipeptide
GO:0089720 caspase binding
GO:0097202 activation of cysteine-type endopeptidase activity
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1904417 positive regulation of xenophagy

Diseases

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Interactions

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