Entity Details

Primary name FADD
Entity type gene
Source Source Link

Details

PrimaryID8772
RefseqGeneNG_027966
SymbolFADD
NameFas associated via death domain
Chromosome11
Location11q13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFADD_HUMAN

GO terms

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GOName
GO:0001822 kidney development
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002020 protease binding
GO:0002821 positive regulation of adaptive immune response
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007166 cell surface receptor signaling pathway
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0016032 viral process
GO:0031264 death-inducing signaling complex
GO:0031265 CD95 death-inducing signaling complex
GO:0032729 positive regulation of interferon-gamma production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032813 tumor necrosis factor receptor superfamily binding
GO:0033077 T cell differentiation in thymus
GO:0033612 receptor serine/threonine kinase binding
GO:0034138 toll-like receptor 3 signaling pathway
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0035877 death effector domain binding
GO:0036462 TRAIL-activated apoptotic signaling pathway
GO:0042104 positive regulation of activated T cell proliferation
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278 response to morphine
GO:0044297 cell body
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045651 positive regulation of macrophage differentiation
GO:0045862 positive regulation of proteolysis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048148 behavioral response to cocaine
GO:0048535 lymph node development
GO:0048536 spleen development
GO:0048538 thymus development
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:0060546 negative regulation of necroptotic process
GO:0070236 negative regulation of activation-induced cell death of T cells
GO:0071260 cellular response to mechanical stimulus
GO:0071550 death-inducing signaling complex assembly
GO:0089720 caspase binding
GO:0097049 motor neuron apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097202 activation of cysteine-type endopeptidase activity
GO:0097342 ripoptosome
GO:0097527 necroptotic signaling pathway
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000454 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FADDFasBioGRID, DIP, IntAct10542291 20935634 7536190 details
FADDNacaBioGRID24901053 details
FADDTnip1DIP19060883 details