Entity Details

Primary name ACTN2
Entity type gene
Source Source Link

Details

PrimaryID88
RefseqGeneNG_009081
SymbolACTN2
Nameactinin alpha 2
Chromosome1
Location1q43
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-08-25
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsACTN2_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002576 platelet degranulation
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0008092 cytoskeletal protein binding
GO:0008307 structural constituent of muscle
GO:0019904 protein domain specific binding
GO:0030018 Z disc
GO:0030035 microspike assembly
GO:0030049 muscle filament sliding
GO:0030175 filopodium
GO:0030274 LIM domain binding
GO:0030374 nuclear receptor coactivator activity
GO:0030864 cortical actin cytoskeleton
GO:0031093 platelet alpha granule lumen
GO:0031143 pseudopodium
GO:0031432 titin binding
GO:0042391 regulation of membrane potential
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043197 dendritic spine
GO:0043267 negative regulation of potassium ion transport
GO:0043268 positive regulation of potassium ion transport
GO:0044325 transmembrane transporter binding
GO:0045214 sarcomere organization
GO:0048041 focal adhesion assembly
GO:0051015 actin filament binding
GO:0051373 FATZ binding
GO:0051695 actin filament uncapping
GO:0055013 cardiac muscle cell development
GO:0070062 extracellular exosome
GO:0070080 titin Z domain binding
GO:0072659 protein localization to plasma membrane
GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway
GO:0098839 postsynaptic density membrane
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:1901017 negative regulation of potassium ion transmembrane transporter activity
GO:1901018 positive regulation of potassium ion transmembrane transporter activity
GO:2000009 negative regulation of protein localization to cell surface
GO:2000310 regulation of NMDA receptor activity
GO:2001137 positive regulation of endocytic recycling
GO:2001259 positive regulation of cation channel activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ACTN2Adam12UniProt10788519 details
ACTN2Tuba1aBioGRID16169070 details
ACTN2Fbxo32BioGRID15489953 details