Entity Details

Primary name SOCS3
Entity type gene
Source Source Link

Details

PrimaryID9021
RefseqGeneNG_016851
SymbolSOCS3
Namesuppressor of cytokine signaling 3
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSOCS3_HUMAN

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0004860 protein kinase inhibitor activity
GO:0005829 cytosol
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0016567 protein ubiquitination
GO:0019221 cytokine-mediated signaling pathway
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0043066 negative regulation of apoptotic process
GO:0043687 post-translational protein modification
GO:0045597 positive regulation of cell differentiation
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity
GO:0050728 negative regulation of inflammatory response
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0060674 placenta blood vessel development
GO:0060707 trophoblast giant cell differentiation
GO:0060708 spongiotrophoblast differentiation
GO:0070102 interleukin-6-mediated signaling pathway
GO:1990830 cellular response to leukemia inhibitory factor

Diseases

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Interactions

6 interactions