Entity Details

Primary name ACVR1B
Entity type gene
Source Source Link

Details

PrimaryID91
RefseqGeneNG_022926
SymbolACVR1B
Nameactivin A receptor type 1B
Chromosome12
Location12q13.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsACV1B_HUMAN

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001701 in utero embryonic development
GO:0001942 hair follicle development
GO:0004674 protein serine/threonine kinase activity
GO:0004675 transmembrane receptor protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016361 activin receptor activity, type I
GO:0018107 peptidyl-threonine phosphorylation
GO:0030308 negative regulation of cell growth
GO:0031625 ubiquitin protein ligase binding
GO:0032924 activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0034711 inhibin binding
GO:0038092 nodal signaling pathway
GO:0043235 receptor complex
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0046545 development of primary female sexual characteristics
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0048185 activin binding
GO:0071363 cellular response to growth factor stimulus
GO:0097191 extrinsic apoptotic signaling pathway
GO:1901165 positive regulation of trophoblast cell migration

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
ACVR1BAcvr2bDIP14966532 details
ACVR1BSmad7BioGRID9738003 details
ACVR1BDok1BioGRID11927552 details
ACVR1BNedd1BioGRID, IntAct26496610 details
ACVR1BZbtb48BioGRID, IntAct26496610 details