Entity Details

Primary name USP8
Entity type gene
Source Source Link

Details

PrimaryID9101
RefseqGeneNG_047101
SymbolUSP8
Nameubiquitin specific peptidase 8
Chromosome15
Location15q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-02-01
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsUBP8_HUMAN

GO terms

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GOName
GO:0000281 mitotic cytokinesis
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007032 endosome organization
GO:0007265 Ras protein signal transduction
GO:0014069 postsynaptic density
GO:0016579 protein deubiquitination
GO:0017124 SH3 domain binding
GO:0019897 extrinsic component of plasma membrane
GO:0030496 midbody
GO:0031313 extrinsic component of endosome membrane
GO:0031647 regulation of protein stability
GO:0032880 regulation of protein localization
GO:0043197 dendritic spine
GO:0045296 cadherin binding
GO:0070536 protein K63-linked deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:0071549 cellular response to dexamethasone stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0098978 glutamatergic synapse
GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission
GO:1990090 cellular response to nerve growth factor stimulus

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
USP8Grap2DIP, MINT12176364 12773374 19523899 details
USP8YwhaeBioGRID17720156 details
USP8Rasgrf1BioGRID11500497 details
USP8Cd2apBioGRID, IntAct26496610 details
USP8Chmp4bBioGRID, IntAct26496610 details