Entity Details

Primary name FPR2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88536
EntryNameFPR2_MOUSE
FullNameFormyl peptide receptor 2
TaxID10090
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated2009-09-01
DateModified2021-06-02

Ontological Relatives

GenesFpr2

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0001934 positive regulation of protein phosphorylation
GO:0002430 complement receptor mediated signaling pathway
GO:0002768 immune response-regulating cell surface receptor signaling pathway
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
GO:0005124 scavenger receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0006954 inflammatory response
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 integral component of membrane
GO:0019722 calcium-mediated signaling
GO:0032930 positive regulation of superoxide anion generation
GO:0038023 signaling receptor activity
GO:0038024 cargo receptor activity
GO:0042742 defense response to bacterium
GO:0043524 negative regulation of neuron apoptotic process
GO:0045089 positive regulation of innate immune response
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0048143 astrocyte activation
GO:0050728 negative regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0050786 RAGE receptor binding
GO:0050918 positive chemotaxis
GO:0051897 positive regulation of protein kinase B signaling
GO:0061903 positive regulation of 1-phosphatidylinositol-3-kinase activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090026 positive regulation of monocyte chemotaxis
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000826 Formyl peptide receptor-relatedFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR027345 Formyl peptide receptor 1/2FamilyFamily

Diseases

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Interactions

0 interactions

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