Entity Details

Primary name AURKB
Entity type gene
Source Source Link

Details

PrimaryID9212
RefseqGene
SymbolAURKB
Nameaurora kinase B
Chromosome17
Location17p13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-02-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsAURKB_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000776 kinetochore
GO:0000779 condensed chromosome, centromeric region
GO:0002903 negative regulation of B cell apoptotic process
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0005876 spindle microtubule
GO:0006468 protein phosphorylation
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007051 spindle organization
GO:0007052 mitotic spindle organization
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007568 aging
GO:0008283 cell population proliferation
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0009838 abscission
GO:0010369 chromocenter
GO:0016570 histone modification
GO:0019900 kinase binding
GO:0030496 midbody
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031616 spindle pole centrosome
GO:0032091 negative regulation of protein binding
GO:0032133 chromosome passenger complex
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032465 regulation of cytokinesis
GO:0032466 negative regulation of cytokinesis
GO:0032467 positive regulation of cytokinesis
GO:0034501 protein localization to kinetochore
GO:0034644 cellular response to UV
GO:0035174 histone serine kinase activity
GO:0036089 cleavage furrow formation
GO:0043988 histone H3-S28 phosphorylation
GO:0044878 mitotic cytokinesis checkpoint signaling
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0051233 spindle midzone
GO:0051256 mitotic spindle midzone assembly
GO:0051973 positive regulation of telomerase activity
GO:0051983 regulation of chromosome segregation
GO:0097431 mitotic spindle pole
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1904355 positive regulation of telomere capping
GO:1905116 positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore
GO:1990023 mitotic spindle midzone

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
AURKBIncenpBioGRID, IntAct11050385 20360068 details
AURKBAurkbBioGRID, IntAct20360068 details
AURKBCdca5BioGRID, IntAct20360068 details
AURKBCdca8BioGRID, IntAct20360068 details
AURKBXpo1IntAct26673895 details
AURKBPrdm16MINT30462309 details
AURKBMecomMINT30462309 details
AURKBBach1BioGRID29459360 details