Entity Details

Primary name VAPB
Entity type gene
Source Source Link

Details

PrimaryID9217
RefseqGeneNG_008073
SymbolVAPB
NameVAMP associated protein B and C
Chromosome20
Location20q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-17
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsVAPB_HUMAN

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007029 endoplasmic reticulum organization
GO:0008017 microtubule binding
GO:0016021 integral component of membrane
GO:0019048 modulation by virus of host process
GO:0019899 enzyme binding
GO:0030148 sphingolipid biosynthetic process
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0033149 FFAT motif binding
GO:0036498 IRE1-mediated unfolded protein response
GO:0042803 protein homodimerization activity
GO:0044790 negative regulation by host of viral release from host cell
GO:0044791 positive regulation by host of viral release from host cell
GO:0044828 negative regulation by host of viral genome replication
GO:0044829 positive regulation by host of viral genome replication
GO:0044830 modulation by host of viral RNA genome replication
GO:0045070 positive regulation of viral genome replication
GO:0045296 cadherin binding
GO:0046725 negative regulation by virus of viral protein levels in host cell
GO:0046982 protein heterodimerization activity
GO:0048487 beta-tubulin binding
GO:0061817 endoplasmic reticulum-plasma membrane tethering
GO:0090114 COPII-coated vesicle budding
GO:0090158 endoplasmic reticulum membrane organization

Diseases

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Interactions

10 interactions

InteractorPartnerSourcesPublicationsLink
VAPBEpha4BioGRID, IntAct18555774 details
VAPBRassf1BioGRID, IntAct20360068 26496610 details
VAPBRmdn3BioGRID, IntAct20360068 26496610 details
VAPBBmpr1aBioGRID, IntAct26496610 details
VAPBRab5cBioGRID, IntAct26496610 details
VAPBPrkacbBioGRID, IntAct26496610 details
VAPBMecomMINT30462309 details
VAPBArhgap30BioGRID, IntAct32203420 details
VAPBKtn1BioGRID26496610 details
VAPBRnf183BioGRID31732153 details