Entity Details

Primary name GDF15
Entity type gene
Source Source Link

Details

PrimaryID9518
RefseqGene
SymbolGDF15
Namegrowth differentiation factor 15
Chromosome19
Location19p13.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsGDF15_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002023 reduction of food intake in response to dietary excess
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 BMP signaling pathway
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
GO:0040015 negative regulation of multicellular organism growth
GO:0042803 protein homodimerization activity
GO:0043410 positive regulation of MAPK cascade
GO:0051897 positive regulation of protein kinase B signaling
GO:0060395 SMAD protein signal transduction
GO:0060400 negative regulation of growth hormone receptor signaling pathway
GO:0070062 extracellular exosome
GO:0070700 BMP receptor binding
GO:1901741 positive regulation of myoblast fusion

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GDF15Cdc37BioGRID, IntAct26496610 details
GDF15Smn1BioGRID, IntAct26496610 details