Entity Details

Primary name CLOCK
Entity type gene
Source Source Link

Details

PrimaryID9575
RefseqGene
SymbolCLOCK
Nameclock circadian regulator
Chromosome4
Location4q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-23
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsCLOCK_HUMAN

GO terms

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GOName
GO:0000077 DNA damage checkpoint signaling
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006473 protein acetylation
GO:0007165 signal transduction
GO:0007283 spermatogenesis
GO:0007623 circadian rhythm
GO:0009648 photoperiodism
GO:0031490 chromatin DNA binding
GO:0032922 circadian regulation of gene expression
GO:0033391 chromatoid body
GO:0042634 regulation of hair cycle
GO:0042752 regulation of circadian rhythm
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0050729 positive regulation of inflammatory response
GO:0050796 regulation of insulin secretion
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051775 response to redox state
GO:0070888 E-box binding
GO:0071479 cellular response to ionizing radiation
GO:1990513 CLOCK-BMAL transcription complex
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000074 regulation of type B pancreatic cell development
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CLOCKCry1BioGRID, DIP, IntAct24737000 26496610 details
CLOCKArntl2DIP24737000 details
CLOCKPer2DIP24737000 details
CLOCKArntlDIP24737000 details