Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Genes

Cubn

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GO	Name
GO:0001701	in utero embryonic development
GO:0005509	calcium ion binding
GO:0005737	cytoplasm
GO:0005765	lysosomal membrane
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005798	Golgi-associated vesicle
GO:0005886	plasma membrane
GO:0005903	brush border
GO:0005905	clathrin-coated pit
GO:0006898	receptor-mediated endocytosis
GO:0007584	response to nutrient
GO:0008203	cholesterol metabolic process
GO:0009617	response to bacterium
GO:0015889	cobalamin transport
GO:0016020	membrane
GO:0016324	apical plasma membrane
GO:0020028	endocytic hemoglobin import into cell
GO:0030135	coated vesicle
GO:0030139	endocytic vesicle
GO:0030492	hemoglobin binding
GO:0030666	endocytic vesicle membrane
GO:0031419	cobalamin binding
GO:0031526	brush border membrane
GO:0032991	protein-containing complex
GO:0038023	signaling receptor activity
GO:0038024	cargo receptor activity
GO:0042366	cobalamin catabolic process
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0042953	lipoprotein transport
GO:0043202	lysosomal lumen
GO:0043235	receptor complex
GO:0045177	apical part of cell
GO:0070062	extracellular exosome

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Domain	Name	Category	Type
IPR000152	EGF-type aspartate/asparagine hydroxylation site	PTM	PTM
IPR000742	EGF-like domain	Domain	Domain
IPR000859	CUB domain	Domain	Domain
IPR001881	EGF-like calcium-binding domain	Domain	Domain
IPR013032	EGF-like, conserved site	Site	Conserved site
IPR018097	EGF-like calcium-binding, conserved site	Site	Conserved site
IPR024731	EGF domain	Domain	Domain
IPR028876	Cubilin	Family	Family
IPR035914	Spermadhesin, CUB domain superfamily	Family	Homologous superfamily

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2 interactions

Interactor	Partner	Sources	Publications	Link
CUBN_MOUSE	HCD2_HUMAN	BioGRID	22496890	details
CUBN_MOUSE	PCLI1_HUMAN	BioGRID	17124247	details