Entity Details

Primary name PARP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88554
EntryNamePARP2_MOUSE
FullNamePoly [ADP-ribose] polymerase 2
TaxID10090
Evidenceevidence at protein level
Length559
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesParp2

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006302 double-strand break repair
GO:0016570 histone modification
GO:0018312 peptidyl-serine ADP-ribosylation
GO:0030592 DNA ADP-ribosylation
GO:0031491 nucleosome binding
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:0090734 site of DNA damage
GO:0097191 extrinsic apoptotic signaling pathway
GO:0140294 NAD DNA ADP-ribosyltransferase activity
GO:1901215 negative regulation of neuron death
GO:1990404 protein ADP-ribosylase activity

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR004102 Poly(ADP-ribose) polymerase, regulatory domainDomainDomain
IPR008893 WGR domainDomainDomain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domainDomainDomain
IPR036616 Poly(ADP-ribose) polymerase, regulatory domain superfamilyFamilyHomologous superfamily
IPR036930 WGR domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions