Entity Details

Primary name MED12
Entity type gene
Source Source Link

Details

PrimaryID9968
RefseqGeneNG_012808
SymbolMED12
Namemediator complex subunit 12
ChromosomeX
LocationXq13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMED12_HUMAN

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001843 neural tube closure
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007492 endoderm development
GO:0007507 heart development
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0014003 oligodendrocyte development
GO:0014044 Schwann cell development
GO:0016020 membrane
GO:0016592 mediator complex
GO:0019827 stem cell population maintenance
GO:0019904 protein domain specific binding
GO:0021510 spinal cord development
GO:0030374 nuclear receptor coactivator activity
GO:0036342 post-anal tail morphogenesis
GO:0042809 vitamin D receptor binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046966 thyroid hormone receptor binding
GO:0048702 embryonic neurocranium morphogenesis
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0061630 ubiquitin protein ligase activity
GO:0090245 axis elongation involved in somitogenesis
GO:1990403 embryonic brain development

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
MED12Med28IntAct15175163 details
MED12Med22BioGRID, IntAct26496610 details
MED12Bag2BioGRID, IntAct26496610 details
MED12JunbBioGRID, IntAct26496610 details
MED12Xpo1IntAct26673895 details