Entity Details

Primary name CUL3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JLV5
EntryNameCUL3_MOUSE
FullNameCullin-3
TaxID10090
Evidenceevidence at protein level
Length768
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesCul3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000209 protein polyubiquitination
GO:0000278 mitotic cell cycle
GO:0000902 cell morphogenesis
GO:0000922 spindle pole
GO:0001701 in utero embryonic development
GO:0001831 trophectodermal cellular morphogenesis
GO:0004842 ubiquitin-protein transferase activity
GO:0005112 Notch binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005827 polar microtubule
GO:0005886 plasma membrane
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007080 mitotic metaphase plate congression
GO:0007229 integrin-mediated signaling pathway
GO:0007369 gastrulation
GO:0016055 Wnt signaling pathway
GO:0016477 cell migration
GO:0016567 protein ubiquitination
GO:0017145 stem cell division
GO:0030030 cell projection organization
GO:0030332 cyclin binding
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031208 POZ domain binding
GO:0031398 positive regulation of protein ubiquitination
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0031463 Cul3-RING ubiquitin ligase complex
GO:0031625 ubiquitin protein ligase binding
GO:0031648 protein destabilization
GO:0032467 positive regulation of cytokinesis
GO:0035024 negative regulation of Rho protein signal transduction
GO:0036126 sperm flagellum
GO:0040016 embryonic cleavage
GO:0043149 stress fiber assembly
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044346 fibroblast apoptotic process
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0048208 COPII vesicle coating
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity
GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system
GO:0072576 liver morphogenesis
GO:0072686 mitotic spindle
GO:1901992 positive regulation of mitotic cell cycle phase transition

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Golgi apparatus
Nucleus

Domains

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DomainNameCategoryType
IPR001373 Cullin, N-terminalDomainDomain
IPR016157 Cullin, conserved siteSiteConserved site
IPR016158 Cullin homology domainDomainDomain
IPR016159 Cullin repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019559 Cullin protein, neddylation domainDomainDomain
IPR036317 Cullin homology domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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