Entity Details

Primary name PIAS4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JM05
EntryNamePIAS4_MOUSE
FullNameE3 SUMO-protein ligase PIAS4
TaxID10090
Evidenceevidence at protein level
Length507
SequenceStatuscomplete
DateCreated2003-09-19
DateModified2021-06-02

Ontological Relatives

GenesPias4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003712 transcription coregulator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007275 multicellular organism development
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0016032 viral process
GO:0016055 Wnt signaling pathway
GO:0016363 nuclear matrix
GO:0016605 PML body
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0031625 ubiquitin protein ligase binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0033235 positive regulation of protein sumoylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0061665 SUMO ligase activity
GO:1902174 positive regulation of keratinocyte apoptotic process
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1990234 transferase complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003034 SAP domainDomainDomain
IPR004181 Zinc finger, MIZ-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR023321 PINIT domainDomainDomain
IPR027224 E3 SUMO-protein ligase PIAS4FamilyFamily
IPR036361 SAP domain superfamilyFamilyHomologous superfamily
IPR038654 PINIT domain superfamilyFamilyHomologous superfamily

Diseases

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