Entity Details

Primary name RABX5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JM13
EntryNameRABX5_MOUSE
FullNameRab5 GDP/GTP exchange factor
TaxID10090
Evidenceevidence at protein level
Length491
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesRabgef1

GO terms

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GOName
GO:0001933 negative regulation of protein phosphorylation
GO:0002686 negative regulation of leukocyte migration
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005730 nucleolus
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006612 protein targeting to membrane
GO:0006897 endocytosis
GO:0008270 zinc ion binding
GO:0031267 small GTPase binding
GO:0031982 vesicle
GO:0032715 negative regulation of interleukin-6 production
GO:0033004 negative regulation of mast cell activation
GO:0043305 negative regulation of mast cell degranulation
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048261 negative regulation of receptor-mediated endocytosis
GO:0050728 negative regulation of inflammatory response
GO:0055037 recycling endosome
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:1900235 negative regulation of Kit signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome
Recycling endosome

Domains

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DomainNameCategoryType
IPR002653 Zinc finger, A20-typeDomainDomain
IPR003123 VPS9 domainDomainDomain
IPR037191 VPS9 domain superfamilyFamilyHomologous superfamily
IPR041545 RABX5, catalytic core helical domainDomainDomain

Diseases

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