Entity Details

Primary name SRF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JM73
EntryNameSRF_MOUSE
FullNameSerum response factor
TaxID10090
Evidenceevidence at protein level
Length504
SequenceStatuscomplete
DateCreated2006-07-11
DateModified2021-06-02

Ontological Relatives

GenesSrf

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001666 response to hypoxia
GO:0001701 in utero embryonic development
GO:0001707 mesoderm formation
GO:0001764 neuron migration
GO:0001829 trophectodermal cell differentiation
GO:0001947 heart looping
GO:0002011 morphogenesis of an epithelial sheet
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0002521 leukocyte differentiation
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007015 actin filament organization
GO:0007160 cell-matrix adhesion
GO:0007369 gastrulation
GO:0007507 heart development
GO:0007616 long-term memory
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0008306 associative learning
GO:0009725 response to hormone
GO:0010669 epithelial structure maintenance
GO:0010735 positive regulation of transcription via serum response element binding
GO:0010736 serum response element binding
GO:0021766 hippocampus development
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb
GO:0030036 actin cytoskeleton organization
GO:0030038 contractile actin filament bundle assembly
GO:0030155 regulation of cell adhesion
GO:0030168 platelet activation
GO:0030220 platelet formation
GO:0030336 negative regulation of cell migration
GO:0030878 thyroid gland development
GO:0030900 forebrain development
GO:0031175 neuron projection development
GO:0031490 chromatin DNA binding
GO:0033561 regulation of water loss via skin
GO:0034097 response to cytokine
GO:0035855 megakaryocyte development
GO:0035912 dorsal aorta morphogenesis
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043149 stress fiber assembly
GO:0043565 sequence-specific DNA binding
GO:0043589 skin morphogenesis
GO:0045059 positive thymic T cell selection
GO:0045214 sarcomere organization
GO:0045597 positive regulation of cell differentiation
GO:0045773 positive regulation of axon extension
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045987 positive regulation of smooth muscle contraction
GO:0046016 positive regulation of transcription by glucose
GO:0046716 muscle cell cellular homeostasis
GO:0048538 thymus development
GO:0048589 developmental growth
GO:0048821 erythrocyte development
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051491 positive regulation of filopodium assembly
GO:0055003 cardiac myofibril assembly
GO:0060218 hematopoietic stem cell differentiation
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060292 long-term synaptic depression
GO:0060324 face development
GO:0060347 heart trabecula formation
GO:0060425 lung morphogenesis
GO:0060532 bronchus cartilage development
GO:0060534 trachea cartilage development
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0061029 eyelid development in camera-type eye
GO:0061145 lung smooth muscle development
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
GO:0070830 bicellular tight junction assembly
GO:0070878 primary miRNA binding
GO:0071333 cellular response to glucose stimulus
GO:0090009 primitive streak formation
GO:0090136 epithelial cell-cell adhesion
GO:0090398 cellular senescence
GO:0098609 cell-cell adhesion
GO:1900222 negative regulation of amyloid-beta clearance
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002100 Transcription factor, MADS-boxDomainDomain
IPR033897 MADS SRF-likeDomainDomain
IPR036879 Transcription factor, MADS-box superfamilyFamilyHomologous superfamily

Diseases

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