Entity Details

Primary name TRXR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9JMH6
EntryNameTRXR1_MOUSE
FullNameThioredoxin reductase 1, cytoplasmic
TaxID10090
Evidenceevidence at protein level
Length613
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesTxnrd1

GO terms

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GOName
GO:0001650 fibrillar center
GO:0001707 mesoderm formation
GO:0004791 thioredoxin-disulfide reductase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006979 response to oxidative stress
GO:0007369 gastrulation
GO:0008283 cell population proliferation
GO:0010942 positive regulation of cell death
GO:0016174 NAD(P)H oxidase H2O2-forming activity
GO:0016259 selenocysteine metabolic process
GO:0033797 selenate reductase activity
GO:0042537 benzene-containing compound metabolic process
GO:0042744 hydrogen peroxide catabolic process
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0045340 mercury ion binding
GO:0045454 cell redox homeostasis
GO:0050660 flavin adenine dinucleotide binding
GO:0070995 NADPH oxidation

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainDomainDomain
IPR006338 Thioredoxin/glutathione reductase selenoproteinFamilyFamily
IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active siteSiteActive site
IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamilyFamilyHomologous superfamily
IPR023753 FAD/NAD(P)-binding domainDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TRXR1_MOUSECAV1_MOUSEMINT19820694 details