Entity Details

Primary name COMT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO88587
EntryNameCOMT_MOUSE
FullNameCatechol O-methyltransferase
TaxID10090
Evidenceevidence at protein level
Length265
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesComt

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0007565 female pregnancy
GO:0007612 learning
GO:0007614 short-term memory
GO:0008171 O-methyltransferase activity
GO:0008210 estrogen metabolic process
GO:0009712 catechol-containing compound metabolic process
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016036 cellular response to phosphate starvation
GO:0016206 catechol O-methyltransferase activity
GO:0030424 axon
GO:0030425 dendrite
GO:0032259 methylation
GO:0032496 response to lipopolysaccharide
GO:0032502 developmental process
GO:0035814 negative regulation of renal sodium excretion
GO:0042135 neurotransmitter catabolic process
GO:0042417 dopamine metabolic process
GO:0042420 dopamine catabolic process
GO:0042424 catecholamine catabolic process
GO:0042493 response to drug
GO:0043197 dendritic spine
GO:0043231 intracellular membrane-bounded organelle
GO:0043627 response to estrogen
GO:0044297 cell body
GO:0045211 postsynaptic membrane
GO:0045963 negative regulation of dopamine metabolic process
GO:0048265 response to pain
GO:0048609 multicellular organismal reproductive process
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050668 positive regulation of homocysteine metabolic process
GO:0051930 regulation of sensory perception of pain
GO:0102084 L-dopa O-methyltransferase activity
GO:0102938 orcinol O-methyltransferase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR002935 Class I-like SAM-dependent O-methyltransferaseFamilyFamily
IPR017128 Catechol O-methyltransferase, eukaryoticFamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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