Entity Details

Primary name SLAF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QUM4
EntryNameSLAF1_MOUSE
FullNameSignaling lymphocytic activation molecule
TaxID10090
Evidenceevidence at protein level
Length343
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSlamf1

GO terms

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GOName
GO:0001779 natural killer cell differentiation
GO:0001787 natural killer cell proliferation
GO:0002232 leukocyte chemotaxis involved in inflammatory response
GO:0002250 adaptive immune response
GO:0002277 myeloid dendritic cell activation involved in immune response
GO:0002725 negative regulation of T cell cytokine production
GO:0006909 phagocytosis
GO:0007155 cell adhesion
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010759 positive regulation of macrophage chemotaxis
GO:0016021 integral component of membrane
GO:0031338 regulation of vesicle fusion
GO:0032689 negative regulation of interferon-gamma production
GO:0032695 negative regulation of interleukin-12 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0038023 signaling receptor activity
GO:0042104 positive regulation of activated T cell proliferation
GO:0042169 SH2 domain binding
GO:0042802 identical protein binding
GO:0045087 innate immune response
GO:0045335 phagocytic vesicle
GO:0046330 positive regulation of JNK cascade
GO:0050790 regulation of catalytic activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:2000349 negative regulation of CD40 signaling pathway
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000556 positive regulation of T-helper 1 cell cytokine production

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR007110 Immunoglobulin-like domainDomainDomain
IPR010407 Signaling lymphocytic activation molecule, N-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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