Entity Details

Primary name SPY2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QXV8
EntryNameSPY2_MOUSE
FullNameProtein sprouty homolog 2
TaxID10090
Evidenceevidence at protein level
Length315
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesSpry2

GO terms

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GOName
GO:0000132 establishment of mitotic spindle orientation
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007605 sensory perception of sound
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016525 negative regulation of angiogenesis
GO:0019901 protein kinase binding
GO:0030324 lung development
GO:0030335 positive regulation of cell migration
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031345 negative regulation of cell projection organization
GO:0031397 negative regulation of protein ubiquitination
GO:0032587 ruffle membrane
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034260 negative regulation of GTPase activity
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042472 inner ear morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043407 negative regulation of MAP kinase activity
GO:0043539 protein serine/threonine kinase activator activity
GO:0045165 cell fate commitment
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048513 animal organ development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway
GO:0051897 positive regulation of protein kinase B signaling
GO:0060425 lung morphogenesis
GO:0060437 lung growth
GO:0060449 bud elongation involved in lung branching
GO:0060541 respiratory system development
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1902747 negative regulation of lens fiber cell differentiation
GO:1990752 microtubule end
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR007875 SproutyFamilyFamily
IPR030780 Protein sprouty homologue 2FamilyFamily

Diseases

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