Entity Details

Primary name FOXE3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QY14
EntryNameFOXE3_MOUSE
FullNameForkhead box protein E3
TaxID10090
Evidenceevidence at protein level
Length288
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesFoxe3

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0002088 lens development in camera-type eye
GO:0002930 trabecular meshwork development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0009653 anatomical structure morphogenesis
GO:0030154 cell differentiation
GO:0042789 mRNA transcription by RNA polymerase II
GO:0043010 camera-type eye development
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0048468 cell development
GO:0050679 positive regulation of epithelial cell proliferation
GO:0061072 iris morphogenesis
GO:0061073 ciliary body morphogenesis
GO:0061303 cornea development in camera-type eye
GO:1902747 negative regulation of lens fiber cell differentiation
GO:2001111 positive regulation of lens epithelial cell proliferation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR018122 Fork head domain conserved site1SiteConserved site
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FOXE3_MOUSERNPS1_MOUSEBioGRID, IntAct20211142 details
FOXE3_MOUSESALL4_MOUSEBioGRID, IntAct20211142 details