Entity Details

Primary name ABCBB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QY30
EntryNameABCBB_MOUSE
FullNameBile salt export pump
TaxID10090
Evidenceevidence at protein level
Length1321
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesAbcb11

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005524 ATP binding
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006631 fatty acid metabolic process
GO:0006855 drug transmembrane transport
GO:0008206 bile acid metabolic process
GO:0008559 ABC-type xenobiotic transporter activity
GO:0009986 cell surface
GO:0015125 bile acid transmembrane transporter activity
GO:0015126 canalicular bile acid transmembrane transporter activity
GO:0015144 carbohydrate transmembrane transporter activity
GO:0015432 ABC-type bile acid transporter activity
GO:0015721 bile acid and bile salt transport
GO:0015722 canalicular bile acid transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016567 protein ubiquitination
GO:0017144 drug metabolic process
GO:0031998 regulation of fatty acid beta-oxidation
GO:0042493 response to drug
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042632 cholesterol homeostasis
GO:0045177 apical part of cell
GO:0046581 intercellular canaliculus
GO:0046618 drug export
GO:0046691 intracellular canaliculus
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0055085 transmembrane transport
GO:0055088 lipid homeostasis
GO:0055091 phospholipid homeostasis
GO:0120189 positive regulation of bile acid secretion
GO:1904251 regulation of bile acid metabolic process

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Endosome
Recycling endosome membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030278 Bile salt export pumpFamilyFamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily
IPR039421 Type 1 protein exporterFamilyFamily

Diseases

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Interactions

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