Entity Details

Primary name XPF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QZD4
EntryNameXPF_MOUSE
FullNameDNA repair endonuclease XPF
TaxID10090
Evidenceevidence at protein level
Length917
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesErcc4

GO terms

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GOName
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0000109 nucleotide-excision repair complex
GO:0000110 nucleotide-excision repair factor 1 complex
GO:0000712 resolution of meiotic recombination intermediates
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0001094 TFIID-class transcription factor complex binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0004520 endodeoxyribonuclease activity
GO:0005634 nucleus
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0008022 protein C-terminus binding
GO:0009411 response to UV
GO:0009650 UV protection
GO:0010506 regulation of autophagy
GO:0032205 negative regulation of telomere maintenance
GO:0033683 nucleotide-excision repair, DNA incision
GO:0034644 cellular response to UV
GO:0042802 identical protein binding
GO:0047485 protein N-terminus binding
GO:0061819 telomeric DNA-containing double minutes formation
GO:0070522 ERCC4-ERCC1 complex
GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1905765 negative regulation of protection from non-homologous end joining at telomere
GO:1905768 negative regulation of double-stranded telomeric DNA binding
GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006166 ERCC4 domainDomainDomain
IPR006167 DNA repair protein XPFFamilyFamily
IPR010994 RuvA domain 2-likeFamilyHomologous superfamily
IPR011335 Restriction endonuclease type II-likeFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
XPF_MOUSEUBC_MOUSEBioGRID28190767 details
XPF_MOUSESLX4_MOUSEBioGRID24726326 details