Entity Details

Primary name AFAD_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9QZQ1
EntryNameAFAD_MOUSE
FullNameAfadin
TaxID10090
Evidenceevidence at protein level
Length1820
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesAfdn

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0007165 signal transduction
GO:0010628 positive regulation of gene expression
GO:0016607 nuclear speck
GO:0021537 telencephalon development
GO:0021987 cerebral cortex development
GO:0022409 positive regulation of cell-cell adhesion
GO:0030054 cell junction
GO:0030274 LIM domain binding
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0031267 small GTPase binding
GO:0032880 regulation of protein localization
GO:0034334 adherens junction maintenance
GO:0036477 somatodendritic compartment
GO:0043296 apical junction complex
GO:0043547 positive regulation of GTPase activity
GO:0044291 cell-cell contact zone
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0045177 apical part of cell
GO:0046930 pore complex
GO:0046931 pore complex assembly
GO:0048854 brain morphogenesis
GO:0048872 homeostasis of number of cells
GO:0050775 positive regulation of dendrite morphogenesis
GO:0050839 cell adhesion molecule binding
GO:0051015 actin filament binding
GO:0060019 radial glial cell differentiation
GO:0060563 neuroepithelial cell differentiation
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0061885 positive regulation of mini excitatory postsynaptic potential
GO:0061951 establishment of protein localization to plasma membrane
GO:0070160 tight junction
GO:0070445 regulation of oligodendrocyte progenitor proliferation
GO:0070830 bicellular tight junction assembly
GO:0090557 establishment of endothelial intestinal barrier
GO:0140059 dendrite arborization
GO:1902414 protein localization to cell junction
GO:1903861 positive regulation of dendrite extension
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin

Subcellular Location

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Subcellular Location
Cell junction

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000253 Forkhead-associated (FHA) domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR002710 Dilute domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR037977 Afadin, cargo binding domainDomainDomain

Diseases

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